Basic leucine zipper and W2 domain-containing protein 2

BZW2
Identifiers
Aliases	BZW2, MST017, MSTP017, HSPC028, basic leucine zipper and W2 domains 2, 5MP1
External IDs	MGI: 1914162; HomoloGene: 8530; GeneCards: BZW2; OMA:BZW2 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	16,706,523 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	36,208,079 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of biceps brachii; ; right ventricle; ; Skeletal muscle tissue of rectus abdominis; ; triceps brachii muscle; ; vastus lateralis muscle; ; myocardium of left ventricle; ; placenta; ; glutes; ; body of tongue; ; deltoid muscle;
	Top expressed in
	ventricular zone; ; genital tubercle; ; ganglionic eminence; ; embryo; ; epiblast; ; embryo; ; extraocular muscle; ; interventricular septum; ; plantaris muscle; ; muscle of thigh;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	cadherin binding; protein binding;
Cellular component	membrane; cytoplasm;
Biological process	cell differentiation; nervous system development; multicellular organism development;
	Sources:Amigo / QuickGO
Orthologs
	28969
	66912
	ENSG00000136261
	ENSMUSG00000020547
	Q9Y6E2
	Q91VK1
	NM_001159767; NM_014038; NM_001362717; NM_001362718; NM_001362719
	NM_025840
	NP_001153239; NP_054757; NP_001349646; NP_001349647; NP_001349648
	NP_080116
	Wikidata
View/Edit Human	View/Edit Mouse

Basic Leucine Zipper and W2 Domain-Containing Protein 2 is a protein that is encoded by the BZW2 gene. It is a eukaryotic translation factor found in species up to bacteria. In animals, it is localized in the cytoplasm and expressed ubiquitously throughout the body. The heart, placenta, skeletal muscle, and hippocampus show higher expression. In various cancers, upregulation tends to lead to higher severity and mortality. It has been found to interact with SARS-CoV-2.