Bacterial outer membrane
| Lipopolysaccharide-assembly, LptC-related | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | LptC | ||||||||
| Pfam | PF06835 | ||||||||
| Pfam clan | CL0259 | ||||||||
| InterPro | IPR010664 | ||||||||
| |||||||||
| Lipopolysaccharide-assembly | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | LptE | ||||||||
| Pfam | PF04390 | ||||||||
| InterPro | IPR007485 | ||||||||
| TCDB | 1.B.42 | ||||||||
| OPM superfamily | 412 | ||||||||
| OPM protein | 4q35 | ||||||||
| |||||||||
The bacterial outer membrane is found in gram-negative bacteria. Gram-negative bacteria form two lipid bilayers in their cell envelopes - an inner membrane (IM) that encapsulates the cytoplasm, and an outer membrane (OM) that encapsulates the periplasm.
The composition of the outer membrane is distinct from that of the inner cytoplasmic cell membrane - among other things, the outer leaflet of the outer membrane of many gram-negative bacteria includes a complex lipopolysaccharide whose lipid portion acts as an endotoxin - and in some bacteria such as E. coli it is linked to the cell's peptidoglycan by Braun's lipoprotein.
Porins can be found in this layer.