Barton–McCombie deoxygenation

Barton–McCombie deoxygenation
Named after Derek Harold Richard Barton
Stuart W. McCombie
Reaction type Organic redox reaction
Identifiers
Organic Chemistry Portal barton-mccombie-reaction
RSC ontology ID RXNO:0000134

The Barton–McCombie deoxygenation is an organic reaction in which a hydroxy functional group in an organic compound is replaced by a hydrogen to give an alkyl group. It is named after British chemists Sir Derek Harold Richard Barton and Stuart W. McCombie.

This deoxygenation reaction is a radical substitution. In the related Barton decarboxylation the reactant is a carboxylic acid.