Benserazide

Benserazide
Clinical data


Other names	Serazide, RO 4-4602
AHFS/Drugs.com	International Drug Names
Pregnancy category	AU: B3
ATC code	None
Identifiers
IUPAC name (RS)-2-Amino-3-hydroxy-N′-(2,3,4-trihydroxybenzyl)propanehydrazide
CAS Number	322-35-0^Y as HCl: 14919-77-8
PubChem CID	2327
IUPHAR/BPS	5150
DrugBank	DB12783 as HCl: DBSALT002687
ChemSpider	2237^Y as HCl: 25109
UNII	762OS3ZEJU as HCl: B66E5RK36Q
KEGG	D03082^Y
ChEBI	CHEBI:64187 as HCl: CHEBI:31262
ChEMBL	ChEMBL1096979^Y as HCl: ChEMBL1255778
CompTox Dashboard (EPA)	DTXSID9022651
Chemical and physical data
Formula	C₁₀H₁₅N₃O₅
Molar mass	257.246 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES NC(CO)C(=O)NNCC1=C(O)C(O)=C(O)C=C1
InChI InChI=1S/C10H15N3O5/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16/h1-2,6,12,14-17H,3-4,11H2,(H,13,18)^Y Key:BNQDCRGUHNALGH-UHFFFAOYSA-N^Y as HCl: InChI=1S/C10H15N3O5.ClH/c11-6(4-14)10(18)13-12-3-5-1-2-7(15)9(17)8(5)16;/h1-2,6,12,14-17H,3-4,11H2,(H,13,18);1H Key:ULFCBIUXQQYDEI-UHFFFAOYSA-N
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Benserazide is a peripherally acting aromatic L-amino acid decarboxylase or DOPA decarboxylase inhibitor, which is unable to cross the blood–brain barrier.

It is on the World Health Organization's List of Essential Medicines.