Benzydamine

Benzydamine
Clinical data
Trade namesMaxtra Gargle, Difflam, Tantum verde
AHFS/Drugs.comInternational Drug Names
Pregnancy
category
  • AU: B2
Routes of
administration
Oral, topical
ATC code
Legal status
Legal status
  • BR: Class C1 (Other controlled substances)
  • UK: P and POM
  • EU: OTC
Pharmacokinetic data
Protein binding<20%
Elimination half-life13 hours
ExcretionKidney
Identifiers
  • 3-(1-benzyl-1H-indazol-3-yloxy)-N,N-dimethylpropan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.010.354
Chemical and physical data
FormulaC19H23N3O
Molar mass309.413 g·mol−1
3D model (JSmol)
  • n2c(OCCCN(C)C)c1ccccc1n2Cc3ccccc3
  • InChI=1S/C19H23N3O/c1-21(2)13-8-14-23-19-17-11-6-7-12-18(17)22(20-19)15-16-9-4-3-5-10-16/h3-7,9-12H,8,13-15H2,1-2H3 Y
  • Key:CNBGNNVCVSKAQZ-UHFFFAOYSA-N Y
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Benzydamine (also known as Tantum Verde and branded in some countries as Maxtra Gargle, Difflam and Septabene), available as the hydrochloride salt, is a locally acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties for pain relief and anti-inflammatory treatment of inflammatory conditions of the mouth and throat. It falls under class of chemicals known as indazole.