Betamethasone dipropionate

Betamethasone dipropionate
Clinical data
Trade names	Diprolene, Sernivo, Diprosone, others
Other names	Betamethasone-17,21-dipropionate
AHFS/Drugs.com	Monograph
MedlinePlus	a682799
License data	US DailyMed: Betamethasone_dipropionate;
Pregnancy; category	AU: B3;
Routes of; administration	Topical
ATC code	A07EA04 (WHO) C05AA05 (WHO) D07AC01 (WHO) D07XC01 (WHO) H02AB01 (WHO) R01AD06 (WHO) R03BA04 (WHO) S01BA06 (WHO) S01CB04 (WHO) S02BA07 (WHO) S03BA03 (WHO) D07CC01 (WHO) S01CA05 (WHO) S03CA06 (WHO) D07BC01 (WHO) S01BB04 (WHO);
Legal status
Legal status	AU: S4 (Prescription only); UK: POM (Prescription only); US: ℞-only;
Identifiers
	IUPAC name [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate;
CAS Number	5593-20-4 ;
PubChem CID	21800;
DrugBank	DBSALT000851 ; DB00443 ;
ChemSpider	20490 ;
UNII	826Y60901U;
KEGG	D01637;
ChEBI	CHEBI:31276 ;
ChEMBL	ChEMBL1200384 ;
CompTox Dashboard (EPA)	DTXSID2022672 ;
ECHA InfoCard	100.024.551
Chemical and physical data
Formula	C28H37FO7
Molar mass	504.595 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(OCC(=O)[C@]3(OC(=O)CC)[C@]2(C[C@H](O)[C@]4(F)[C@@]/1(\C(=C/C(=O)\C=C\1)CC[C@H]4[C@@H]2C[C@@H]3C)C)C)CC;
	InChI InChI=1S/C28H37FO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1 ; Key:CIWBQSYVNNPZIQ-XYWKZLDCSA-N ;
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Betamethasone dipropionate is a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties. It is applied as a topical cream, ointment, lotion or gel (Diprolene) to treat itching and other skin conditions such as eczema. Minor side effects include dry skin and mild, temporary stinging when applied. Betamethasone dipropionate is a "super high potency" corticosteroid used to treat inflammatory skin conditions such as dermatitis, eczema and psoriasis. It is a synthetic analog of the adrenal corticosteroids. Although its exact mechanism of action is not known, it is effective when applied topically to cortico-responsive inflammatory dermatoses. It is available as a generic medication.