BioGRID
| Content | |
|---|---|
| Description | BioGRID is a biomedical interaction repository with data compiled through comprehensive curation efforts. |
| Data types captured | Protein Interactions, Genetic Interactions, Chemical Interactions, Post-Translational Modifications. |
| Organisms | 80 |
| Contact | |
| Research center | Université de Montréal, Princeton University, Mount Sinai Hospital (Toronto) |
| Laboratory | Institut de Recherche en Immunologie et en Cancérologie, Lewis-Sigler Institute for Integrative Genomics, Lunenfeld-Tanenbaum Research Institute |
| Authors | Lorrie Boucher, Ashton Breitkreutz, Bobby-Joe Breitkreutz, Christie Chang, Andrew Chatr-Aryamontri, Kara Dolinski, Sven Heinicke, Nadine Kolas, Lara O'Donnell, Sara Oster, Rose Oughtred, Jennifer Rust, Adnane Sellam, Chris Stark, Jean Tang, Chandra Theesfeld, Mike Tyers. |
| Primary citation | Stark & al. (2006) |
| Access | |
| Data format | Custom flat files, PSI-MI, MITAB |
| Website | thebiogrid |
| Download URL | downloads |
| Web service URL | Yes - wiki |
| Tools | |
| Web | Advanced search, integrated network viewer, custom downloads, bulk retrieval/download |
| Miscellaneous | |
| Versioning | Yes |
| Data release frequency | Monthly (4 Weeks) |
| Version | 4.2.193; 1 January 2021 |
| Curation policy | Yes - manual; Also focused curation efforts. |
| Bookmarkable entities | Yes - both individual results and searches, |
The Biological General Repository for Interaction Datasets (BioGRID) is a curated biological database of protein-protein interactions, genetic interactions, chemical interactions, and post-translational modifications created in 2003 (originally referred to as simply the General Repository for Interaction Datasets (GRID) by Mike Tyers, Bobby-Joe Breitkreutz, and Chris Stark at the Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital. It strives to provide a comprehensive curated resource for all major model organism species while attempting to remove redundancy to create a single mapping of data. Users of The BioGRID can search for their protein, chemical or publication of interest and retrieve annotation, as well as curated data as reported, by the primary literature and compiled by in house large-scale curation efforts. The BioGRID is hosted in Toronto, Ontario, Canada and Dallas, Texas, United States and is partnered with the Saccharomyces Genome Database, FlyBase, WormBase, PomBase, and the Alliance of Genome Resources. The BioGRID is funded by the NIH and CIHR. BioGRID is an observer member of the International Molecular Exchange Consortium (IMEx).