C11orf54

C11orf54
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1XCR
Identifiers
Aliases	C11orf54, PTD012, PTOD012, chromosome 11 open reading frame 54
External IDs	OMIM: 615810; MGI: 1918234; HomoloGene: 8531; GeneCards: C11orf54; OMA:C11orf54 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	93,764,749 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	15,217,744 bp
RNA expression pattern
	Top expressed in
	renal medulla; ; human kidney; ; mucosa of ileum; ; jejunal mucosa; ; liver; ; mucosa of paranasal sinus; ; pancreatic epithelial cell; ; Skeletal muscle tissue of biceps brachii; ; metanephros; ; retinal pigment epithelium;
	Top expressed in
	parotid gland; ; brown adipose tissue; ; left lobe of liver; ; human kidney; ; transitional epithelium of urinary bladder; ; olfactory epithelium; ; jejunum; ; tunica adventitia of aorta; ; left colon; ; duodenum;
	More reference expression data
	n/a
Gene ontology
Molecular function	zinc ion binding; protein binding; hydrolase activity; hydrolase activity, acting on ester bonds; metal ion binding;
Cellular component	extracellular exosome; nucleus; nucleoplasm; nuclear body;
Biological process	metabolism;
	Sources:Amigo / QuickGO
Orthologs
	28970
	70984
	ENSG00000182919
	ENSMUSG00000031938
	Q9H0W9
	Q91V76
NM_001286067; NM_001286068; NM_001286069; NM_001286070; NM_001286071;
	NM_014039; NM_001351985; NM_001351986; NM_001351988; NM_001351989; NM_001351990; NM_001351991; NM_001351992; NM_001351993; NM_001351987; NM_001369406
	NM_001199484; NM_001199485; NM_133732; NM_001359258
NP_001272996; NP_001272997; NP_001272998; NP_001272999; NP_001273000;
	NP_054758; NP_001338914; NP_001338915; NP_001338916; NP_001338917; NP_001338918; NP_001338919; NP_001338920; NP_001338921; NP_001338922; NP_001356335
	NP_001186413; NP_001186414; NP_598493; NP_001346187
	Wikidata
View/Edit Human	View/Edit Mouse

Chromosome 11 open reading frame 54 (C11orf54) is a protein that in humans is encoded by the C11orf54 gene. The "Homo sapiens" gene, C11orf54 is also known as PTD012 and PTOD12. C11orf54 exhibits hydrolase activity on p-nitrophenyl acetate and acts on ester bonds, though the overall function is still not fully understood by the scientific community. The protein is highly conserved with the most distant homolog found is in bacteria.