C12orf29

C12orf29
Identifiers
Aliases	C12orf29, chromosome 12 open reading frame 29, LOC91298, FLJ38158, MGC102978, DKFZp313K0436, DKFZp434N2030, DKFZp686L04169
External IDs	MGI: 1921197; HomoloGene: 18409; GeneCards: C12orf29; OMA:C12orf29 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	88,050,160 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	100,426,285 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; Brodmann area 23; ; oocyte; ; skin of thigh; ; oral cavity; ; pars reticulata; ; palpebral conjunctiva; ; secondary oocyte; ; human penis; ; entorhinal cortex;
	Top expressed in
	spermatocyte; ; spermatid; ; cumulus cell; ; lobe of cerebellum; ; neural layer of retina; ; facial motor nucleus; ; genital tubercle; ; cerebellar vermis; ; intercostal muscle; ; habenula;
	More reference expression data
	n/a
Orthologs
	91298
	68281
	ENSG00000133641
	ENSMUSG00000046567
	Q8N999
	Q8BHN7
	NM_001009894
	NM_175128
	NP_001009894
	NP_780337
	Wikidata
View/Edit Human	View/Edit Mouse

C12orf29 is a protein that in humans is encoded by chromosome 12 open reading frame 29. The gene is ubiquitously expressed in various tissues. The protein has 325 amino acids. The biological process of C12orf29 has been annotated as hematopoietic progenitor cell differentiation. The molecular and cellular functions of C12orf29 gene have not yet well understood by the scientific community.

Research suggested that C12orf29 is a potential structural protein in skeletal tissue with a role in the extracellular matrix of articular and growth cartilage. It has increased expression in osteosarcoma (OS) tumor cells and other tumor cells, and it could be a potential biomarker for detecting osteosarcoma.