C2orf80

C2orf80
Identifiers
Aliases	C2orf80, GONDA1, chromosome 2 open reading frame 80
External IDs	OMIM: 615536; MGI: 2138198; HomoloGene: 129674; GeneCards: C2orf80; OMA:C2orf80 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	208,190,030 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	65,123,214 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; middle temporal gyrus; ; dorsolateral prefrontal cortex; ; prefrontal cortex; ; anterior cingulate cortex; ; Brodmann area 23; ; Brodmann area 9; ; Amygdala; ; nucleus accumbens; ; right frontal lobe;
	Top expressed in
	right kidney; ; otolith organ; ; utricle; ; gastrula; ; lumbar subsegment of spinal cord; ; human kidney; ; zygote; ; secondary oocyte; ; granulocyte; ; dentate gyrus of hippocampal formation granule cell;
	More reference expression data
	n/a
Orthologs
	389073
	98303
	ENSG00000188674
	ENSMUSG00000044816
	Q0P641
	Q8C3M9
	NM_001099334
	NM_001285881; NM_001285882; NM_175293
	NP_001092804
	NP_001272810; NP_001272811; NP_780502
	Wikidata
View/Edit Human	View/Edit Mouse

C2orf80 (chromosome 2 open reading frame 80) is a protein that, in humans, is encoded by the c2orf80 gene. The gene c2orf80 also goes by the alias GONDA1 (gonad development associated 1). In humans, c2orf80 is exclusively expressed in the brain. While relatively little is known about the function of c2orf80, medical studies have shown a strong association between variations in c2orf80 and IDH-mutant gliomas, 46,XY gonadal dysgenesis, and a possible association with blood pressure.