C6orf136

C6orf136
Identifiers
Aliases	C6orf136, chromosome 6 open reading frame 136
External IDs	MGI: 1916912; HomoloGene: 17027; GeneCards: C6orf136; OMA:C6orf136 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	30,653,210 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	36,208,323 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; primary visual cortex; ; cerebellar cortex; ; cerebellar hemisphere; ; apex of heart; ; right hemisphere of cerebellum; ; superior frontal gyrus; ; Brodmann area 9; ; right frontal lobe; ; rectum;
	Top expressed in
	Paneth cell; ; digastric muscle; ; sternocleidomastoid muscle; ; temporal muscle; ; triceps brachii muscle; ; right ventricle; ; substantia nigra; ; myocardium of ventricle; ; thoracic diaphragm; ; motor neuron;
	More reference expression data
	n/a
Orthologs
	221545
	69662
ENSG00000233641; ENSG00000233164; ENSG00000237012; ENSG00000237100; ENSG00000204564;
	ENSG00000224120; ENSG00000206487
	ENSMUSG00000050705
	Q5SQH8
	n/a
	NM_001109938; NM_001161376; NM_145029
	NM_001033630
	NP_001103408; NP_001154848; NP_659466
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

C6orf136 (Chromosome 6 Open Reading Frame 136) is a protein in humans (Homo sapiens) encoded by the C6orf136 gene. The gene is conserved in mammals, mollusks, as well some porifera. While the function of the gene is currently unknown, C6orf136 has been shown to be hypermethylated in response to FOXM1 expression in Head Neck Squamous Cell Carcinoma (HNSCC) tissue cells. Additionally, elevated expression of C6orf136 has been associated with improved survival rates in patients with bladder cancer. C6orf136 has three known isoforms.