CACNB3

CACNB3
Identifiers
Aliases	CACNB3, CAB3, CACNLB3, calcium voltage-gated channel auxiliary subunit beta 3
External IDs	OMIM: 601958; MGI: 103307; HomoloGene: 20187; GeneCards: CACNB3; OMA:CACNB3 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	48,828,941 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	98,542,410 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; frontal pole; ; right uterine tube; ; right frontal lobe; ; right ovary; ; left ovary; ; right hemisphere of cerebellum; ; endothelial cell; ; prefrontal cortex; ; stromal cell of endometrium;
	Top expressed in
	habenula; ; superior frontal gyrus; ; primary visual cortex; ; entorhinal cortex; ; dentate gyrus of hippocampal formation granule cell; ; perirhinal cortex; ; CA3 field; ; olfactory epithelium; ; lumbar spinal ganglion; ; external carotid artery;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein kinase binding; voltage-gated ion channel activity; voltage-gated calcium channel activity; high voltage-gated calcium channel activity; calcium channel activity; protein binding; calcium channel regulator activity;
Cellular component	apical plasma membrane; membrane; cytosol; plasma membrane; voltage-gated calcium channel complex; L-type voltage-gated calcium channel complex; cytoplasm;
Biological process	membrane depolarization; regulation of ion transmembrane transport; ion transport; regulation of voltage-gated calcium channel activity; neuromuscular junction development; calcium ion transmembrane transport; calcium ion transport; regulation of membrane repolarization during action potential; calcium ion transport into cytosol; protein localization to plasma membrane; chemical synaptic transmission; calcium ion transmembrane transport via high voltage-gated calcium channel; detection of mechanical stimulus involved in sensory perception of pain; positive regulation of protein targeting to membrane; cellular response to oxygen-glucose deprivation; negative regulation of voltage-gated calcium channel activity; positive regulation of voltage-gated calcium channel activity; positive regulation of high voltage-gated calcium channel activity; regulation of membrane hyperpolarization; negative regulation of detection of mechanical stimulus involved in sensory perception of touch; positive regulation of excitatory postsynaptic potential; T cell receptor signaling pathway; cardiac conduction;
	Sources:Amigo / QuickGO
Orthologs
	784
	12297
	ENSG00000167535
	ENSMUSG00000003352
	P54284
	P54285
	NM_000725; NM_001206915; NM_001206916; NM_001206917
	NM_001044741; NM_001286226; NM_007581; NM_001356543
	NP_000716; NP_001193844; NP_001193845; NP_001193846
	NP_001038206; NP_001273155; NP_031607; NP_001343472
	Wikidata
View/Edit Human	View/Edit Mouse

Voltage-dependent L-type calcium channel subunit beta-3 is a protein that in humans is encoded by the CACNB3 gene.