CADM3

CADM3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1Z9M
Identifiers
Aliases	CADM3, BIgR, IGSF4B, NECL1, Necl-1, TSLL1, synCAM3, cell adhesion molecule 3, CMT2FF
External IDs	OMIM: 609743; MGI: 2137858; HomoloGene: 10919; GeneCards: CADM3; OMA:CADM3 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	159,203,313 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	173,195,261 bp
RNA expression pattern
	Top expressed in
	cerebellar hemisphere; ; right hemisphere of cerebellum; ; right frontal lobe; ; tibial nerve; ; anterior cingulate cortex; ; nucleus accumbens; ; Brodmann area 9; ; prefrontal cortex; ; sural nerve; ; Amygdala;
	Top expressed in
	cerebellar cortex; ; neural layer of retina; ; superior frontal gyrus; ; primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; piriform cortex; ; lobe of cerebellum; ; cerebellar vermis; ; motor neuron; ; sciatic nerve;
	More reference expression data
	n/a
Gene ontology
Molecular function	signaling receptor binding; protein homodimerization activity; cell adhesion molecule binding;
Cellular component	integral component of membrane; cell junction; plasma membrane; integral component of plasma membrane; membrane; cell-cell junction; parallel fiber to Purkinje cell synapse; integral component of presynaptic membrane;
Biological process	protein localization; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; cell adhesion; cell recognition; adherens junction organization; homophilic cell adhesion via plasma membrane adhesion molecules;
	Sources:Amigo / QuickGO
Orthologs
	57863
	94332
	ENSG00000162706
	ENSMUSG00000005338
	Q8N126
	Q99N28
	NM_021189; NM_001127173; NM_001346510
	NM_053199
	NP_001120645; NP_001333439; NP_067012
	NP_444429
	Wikidata
View/Edit Human	View/Edit Mouse

Cell adhesion molecule 3 is a protein that in humans is encoded by the CADM3 gene.

IGSF4B is a brain-specific protein related to the calcium-independent cell-cell adhesion molecules known as nectins (see PVRL3; MIM 607147) (Kakunaga et al., 2005).