CALHM1

CALHM1
Identifiers
Aliases	CALHM1, FAM26C, calcium homeostasis modulator 1
External IDs	OMIM: 612234; MGI: 3643383; HomoloGene: 55508; GeneCards: CALHM1; OMA:CALHM1 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	103,458,900 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	47,132,693 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; prefrontal cortex; ; external globus pallidus; ; pars compacta; ; superior vestibular nucleus; ; Brodmann area 9; ; right frontal lobe; ; occipital lobe; ; Brodmann area 23; ; superior frontal gyrus;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	voltage-gated calcium channel activity; calcium activated cation channel activity; calcium channel activity; voltage-gated ion channel activity; identical protein binding;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; membrane; plasma membrane; integral component of plasma membrane; endoplasmic reticulum;
Biological process	sensory perception of umami taste; ATP transport; regulation of ion transmembrane transport; cation transport; ion transport; sensory perception of bitter taste; calcium ion transmembrane transport; sensory perception of sweet taste; protein homooligomerization; sensory perception of taste; calcium ion transport;
	Sources:Amigo / QuickGO
Orthologs
	255022
	546729
	ENSG00000185933
	ENSMUSG00000079258
	Q8IU99
	D3Z291
	NM_001001412
	NM_001081271
	NP_001001412
	NP_001074740
	Wikidata
View/Edit Human	View/Edit Mouse

Calcium homeostasis modulator 1 (CALHM1) is a pore-forming subunit of a voltage-gated ion channel and a voltage-gated ATP channel that in humans is encoded by the CALHM1 gene.