CAMKK2

CAMKK2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2ZV2
Identifiers
Aliases	CAMKK2, CAMKK, CAMKKB, calcium/calmodulin-dependent protein kinase kinase 2, calcium/calmodulin dependent protein kinase kinase 2
External IDs	OMIM: 615002; MGI: 2444812; HomoloGene: 32756; GeneCards: CAMKK2; OMA:CAMKK2 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	121,298,308 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	122,917,472 bp
RNA expression pattern
	Top expressed in
	cerebellar cortex; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; cerebellar vermis; ; paraflocculus of cerebellum; ; right frontal lobe; ; prefrontal cortex; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; orbitofrontal cortex;
	Top expressed in
	motor neuron; ; medullary collecting duct; ; barrel cortex; ; superior frontal gyrus; ; primary motor cortex; ; trigeminal ganglion; ; dorsal striatum; ; visual cortex; ; Rostral migratory stream; ; primary visual cortex;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; calcium ion binding; protein kinase activity; calmodulin binding; kinase activity; protein serine/threonine kinase activity; protein tyrosine kinase activity; ATP binding; calmodulin-dependent protein kinase activity;
Cellular component	cell projection; intracellular anatomical structure; nucleus; cytoplasm; cytosol; nucleoplasm;
Biological process	phosphorylation; MAPK cascade; positive regulation of transcription, DNA-templated; protein phosphorylation; protein autophosphorylation; regulation of protein kinase activity; calcium-mediated signaling; peptidyl-tyrosine phosphorylation; positive regulation of protein phosphorylation; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; cellular response to reactive oxygen species; positive regulation of protein kinase activity; CAMKK-AMPK signaling cascade; positive regulation of autophagy of mitochondrion;
	Sources:Amigo / QuickGO
Orthologs
	10645
	207565
	ENSG00000110931
	ENSMUSG00000029471
	Q96RR4
	Q8C078
NM_001270485; NM_001270486; NM_006549; NM_153499; NM_153500;
	NM_172214; NM_172215; NM_172216; NM_172226
	NM_001199676; NM_145358
NP_001257414; NP_001257415; NP_006540; NP_705719; NP_705720;
	NP_757363; NP_757364; NP_757365; NP_757380; NP_757365.1
	NP_001186605; NP_663333
	Wikidata
View/Edit Human	View/Edit Mouse

Calcium/calmodulin-dependent protein kinase kinase 2 is an enzyme that in humans is encoded by the CAMKK2 gene.