CAP1

CAP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1K8F
Identifiers
Aliases	CAP1, CAP, CAP1-PEN, CAP, adenylate cyclase-associated protein 1 (yeast), adenylate cyclase associated protein 1
External IDs	OMIM: 617801; MGI: 88262; HomoloGene: 74572; GeneCards: CAP1; OMA:CAP1 - orthologs
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	122,779,849 bp
RNA expression pattern
	n/a
	Top expressed in
	granulocyte; ; lateral septal nucleus; ; dentate gyrus of hippocampal formation granule cell; ; superior frontal gyrus; ; transitional epithelium of urinary bladder; ; tibiofemoral joint; ; cervix; ; yolk sac; ; decidua; ; lip;
	; ;
	More reference expression data
Gene ontology
Molecular function	adenylate cyclase binding; actin binding;
Cellular component	cytoplasm; plasma membrane; extracellular exosome; membrane; focal adhesion; cortical actin cytoskeleton; extracellular region; extracellular space; azurophil granule lumen;
Biological process	establishment or maintenance of cell polarity; ameboidal-type cell migration; receptor-mediated endocytosis; actin cytoskeleton organization; cytoskeleton organization; signal transduction; activation of adenylate cyclase activity; cell morphogenesis; actin polymerization or depolymerization; neutrophil degranulation; regulation of adenylate cyclase activity;
	Sources:Amigo / QuickGO
Orthologs
	10487
	12331
	ENSG00000131236
	ENSMUSG00000028656
	Q01518; Q5T0R9
	P40124
	NM_001105530; NM_006367; NM_001330502
	NM_001301067; NM_007598; NM_001358035; NM_001358036
NP_001099000; NP_001317431; NP_006358; NP_001337404; NP_001337405;
	NP_001337406; NP_001337407; NP_001337408; NP_001337409; NP_001337410; NP_001337411; NP_001337412; NP_001337413; NP_001337414
	NP_001287996; NP_031624; NP_001344964; NP_001344965
	Wikidata
View/Edit Human	View/Edit Mouse

Adenylyl cyclase-associated protein 1 is an enzyme that in humans is encoded by the CAP1 gene.

The protein encoded by this gene is related to the Saccharomyces cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin.