CAPRIN2

CAPRIN2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4OUL, 4OUM
Identifiers
Aliases	CAPRIN2, C1QDC1, EEG-1, EEG1, RNG140, caprin family member 2
External IDs	OMIM: 610375; MGI: 2448541; HomoloGene: 11393; GeneCards: CAPRIN2; OMA:CAPRIN2 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	30,754,951 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	148,797,735 bp
RNA expression pattern
	Top expressed in
	spinal ganglia; ; cerebellar vermis; ; right hemisphere of cerebellum; ; trigeminal ganglion; ; testicle; ; sural nerve; ; lateral nuclear group of thalamus; ; pars compacta; ; pars reticulata; ; external globus pallidus;
	Top expressed in
	lens; ; epithelium of lens; ; zygote; ; primary oocyte; ; secondary oocyte; ; tail of embryo; ; neural layer of retina; ; lumbar spinal ganglion; ; supraoptic nucleus; ; paraventricular nucleus of hypothalamus;
	More reference expression data
	n/a
Gene ontology
Molecular function	signaling receptor binding; protein binding; RNA binding; metal ion binding;
Cellular component	centrosome; receptor complex; nucleus; mitochondrion; cytoplasm; cytosol; plasma membrane; membrane;
Biological process	positive regulation of canonical Wnt signaling pathway; regulation of growth; cell differentiation; negative regulation of translation; positive regulation of protein binding; negative regulation of cell growth; positive regulation of peptidyl-serine phosphorylation; positive regulation of transcription by RNA polymerase II; positive regulation of dendrite morphogenesis; positive regulation of dendritic spine morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	65981
	232560
	ENSG00000110888
	ENSMUSG00000030309
	Q6IMN6
	Q05A80
NM_001002259; NM_001206856; NM_023925; NM_032156; NM_001319842;
	NM_001319843; NM_001319844; NM_001319845; NM_001319846
	NM_001301351; NM_181541
NP_001002259; NP_001193785; NP_001306771; NP_001306772; NP_001306773;
	NP_001306774; NP_001306775; NP_076414; NP_115532
	NP_001288280; NP_853519
	Wikidata
View/Edit Human	View/Edit Mouse

caprin family member 2, also known as CAPRIN2, is a human gene.

The protein encoded by this gene may be involved in the transitioning of erythroblasts from a highly proliferative state to a terminal phase of differentiation. High level expression of the encoded protein can lead to apoptosis. Several transcript variants encoding different isoforms have been found for this gene.