Capping protein (actin filament) muscle Z-line, alpha 1

CAPZA1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1MQ1, 1MWN
Identifiers
Aliases	CAPZA1, CAPPA1, CAPZ, CAZ1, capping actin protein of muscle Z-line alpha subunit 1, capping actin protein of muscle Z-line subunit alpha 1
External IDs	OMIM: 601580; MGI: 106227; HomoloGene: 24376; GeneCards: CAPZA1; OMA:CAPZA1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	112,671,616 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	104,771,821 bp
RNA expression pattern
	Top expressed in
	epithelium of nasopharynx; ; gingival epithelium; ; bone marrow; ; germinal epithelium; ; mucosa of pharynx; ; monocyte; ; trabecular bone; ; skin of thigh; ; oral cavity; ; bone marrow cells;
	Top expressed in
	granulocyte; ; tail of embryo; ; thymus; ; spermatocyte; ; yolk sac; ; genital tubercle; ; ventricular zone; ; ileum; ; stomach; ; neural tube;
	More reference expression data
	n/a
Gene ontology
Molecular function	actin binding; protein binding; cadherin binding; actin filament binding;
Cellular component	F-actin capping protein complex; cytoplasm; extracellular region; cytosol; WASH complex; extracellular exosome; cytoskeleton; actin cytoskeleton; actin cortical patch;
Biological process	barbed-end actin filament capping; innate immune response; blood coagulation; actin filament capping; endoplasmic reticulum to Golgi vesicle-mediated transport; antigen processing and presentation of exogenous peptide antigen via MHC class II; interleukin-12-mediated signaling pathway; cell junction assembly; actin cytoskeleton organization; protein-containing complex assembly;
	Sources:Amigo / QuickGO
Orthologs
	829
	12340
	ENSG00000116489
	ENSMUSG00000070372
	P52907
	P47753
	NM_006135
	NM_009797; NM_001355044
	NP_006126
	NP_033927; NP_001341973
	Wikidata
View/Edit Human	View/Edit Mouse

F-actin-capping protein subunit alpha-1 is a protein that in humans is encoded by the CAPZA1 gene.

CAPZA1 is a member of the F-actin capping protein alpha subunit family. This gene encodes the alpha subunit of the barbed-end actin binding protein.