CAPZA2

CAPZA2
Identifiers
Aliases	CAPZA2, CAPPA2, CAPZ, capping actin protein of muscle Z-line alpha subunit 2, capping actin protein of muscle Z-line subunit alpha 2
External IDs	OMIM: 601571; MGI: 106222; HomoloGene: 55956; GeneCards: CAPZA2; OMA:CAPZA2 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	116,922,049 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	17,666,971 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; monocyte; ; Skeletal muscle tissue of rectus abdominis; ; biceps brachii; ; right ventricle; ; Achilles tendon; ; Skeletal muscle tissue of biceps brachii; ; myocardium; ; tail of epididymis; ; mucosa of sigmoid colon;
	Top expressed in
	triceps brachii muscle; ; vastus lateralis muscle; ; temporal muscle; ; sternocleidomastoid muscle; ; muscle of thigh; ; stroma of bone marrow; ; knee joint; ; Region I of hippocampus proper; ; ankle; ; digastric muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	actin binding; actin filament binding; protein binding;
Cellular component	F-actin capping protein complex; extracellular region; cytosol; cortical cytoskeleton; extracellular exosome; membrane; brush border; actin cytoskeleton; actin cortical patch;
Biological process	barbed-end actin filament capping; innate immune response; blood coagulation; actin filament capping; endoplasmic reticulum to Golgi vesicle-mediated transport; antigen processing and presentation of exogenous peptide antigen via MHC class II; actin cytoskeleton organization; protein-containing complex assembly;
	Sources:Amigo / QuickGO
Orthologs
	830
	12343
	ENSG00000198898
	ENSMUSG00000015733
	P47755
	P47754
	NM_006136
	NM_007604
	NP_006127
	NP_031630
	Wikidata
View/Edit Human	View/Edit Mouse

F-actin-capping protein subunit alpha-2 also known as CapZ-alpha2 is a protein that in humans is encoded by the CAPZA2 gene.