CARMIL1

CARMIL1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3LK2, 3LK3
Identifiers
Aliases	CARMIL1, CARMIL, CARMIL1a, LRRC16, dJ501N12.1, dJ501N12.5, LRRC16A, leucine rich repeat containing 16A, capping protein regulator and myosin 1 linker 1
External IDs	OMIM: 609593; MGI: 1915982; HomoloGene: 9757; GeneCards: CARMIL1; OMA:CARMIL1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	25,620,530 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	24,464,778 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; Achilles tendon; ; mucosa of transverse colon; ; left coronary artery; ; right hemisphere of cerebellum; ; thoracic aorta; ; Descending thoracic aorta; ; ascending aorta; ; testicle;
	Top expressed in
	zygote; ; secondary oocyte; ; molar; ; saccule; ; primary oocyte; ; otic vesicle; ; spermatid; ; vestibular sensory epithelium; ; otic placode; ; medullary collecting duct;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein-containing complex binding; protein binding;
Cellular component	filamentous actin; cell projection; membrane; plasma membrane; macropinosome; cell leading edge; extracellular exosome; cytoskeleton; nucleus; lamellipodium; cytoplasm; cytosol; nuclear speck;
Biological process	barbed-end actin filament uncapping; positive regulation of lamellipodium organization; negative regulation of barbed-end actin filament capping; positive regulation of actin filament polymerization; ruffle organization; actin filament organization; positive regulation of cell migration; actin filament network formation; blood coagulation; positive regulation of substrate adhesion-dependent cell spreading; macropinocytosis; urate metabolic process; cell migration; positive regulation of stress fiber assembly; lamellipodium assembly;
	Sources:Amigo / QuickGO
Orthologs
	55604
	68732
	ENSG00000079691
	ENSMUSG00000021338
	Q5VZK9
	Q6EDY6
	NM_001173977; NM_017640
	NM_026825; NM_177807; NM_001311122; NM_001384122
	NP_001167448; NP_060110
	NP_001298051; NP_081101; NP_001371051
	Wikidata
View/Edit Human	View/Edit Mouse

CARMIL1 is a protein that in humans is encoded by the CARMIL1 gene. The gene is also known as LRRC16, LRRC16A, CARMIL, or CARMIL1a.