CASC3

CASC3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2HYI, 2J0Q, 2J0S, 2J0U, 2XB2, 3EX7
Identifiers
Aliases	CASC3, BTZ, MLN51, cancer susceptibility candidate 3, cancer susceptibility 3, exon junction complex subunit, CASC3 exon junction complex subunit
External IDs	OMIM: 606504; MGI: 2179723; HomoloGene: 7208; GeneCards: CASC3; OMA:CASC3 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	40,172,171 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	98,724,640 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; middle frontal gyrus; ; gastric mucosa; ; ganglionic eminence; ; paraflocculus of cerebellum; ; body of uterus; ; Brodmann area 10; ; popliteal artery; ; tibial arteries; ; ventricular zone;
	Top expressed in
	tail of embryo; ; neural layer of retina; ; granulocyte; ; genital tubercle; ; ventricular zone; ; epiblast; ; cumulus cell; ; ankle joint; ; yolk sac; ; Rostral migratory stream;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; identical protein binding; enzyme binding; ubiquitin protein ligase binding; RNA binding;
Cellular component	cytoplasm; cytosol; nuclear speck; exon-exon junction complex; perinuclear region of cytoplasm; nucleus; nucleoplasm; nuclear membrane; cytoplasmic stress granule; dendrite; cytoplasmic ribonucleoprotein granule; cell projection; ribonucleoprotein complex; U2-type catalytic step 1 spliceosome; spliceosomal complex;
Biological process	mRNA transport; mRNA processing; intracellular mRNA localization; RNA splicing; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; regulation of translation; mRNA splicing, via spliceosome; RNA export from nucleus; termination of RNA polymerase II transcription; mRNA export from nucleus; mRNA 3'-end processing; transport; biological process;
	Sources:Amigo / QuickGO
Orthologs
	22794
	192160
	ENSG00000108349
	ENSMUSG00000078676
	O15234
	Q8K3W3
	NM_007359
	NM_138660
	NP_031385
	NP_619601
	Wikidata
View/Edit Human	View/Edit Mouse

Protein CASC3 is a protein that in humans is encoded by the CASC3 gene.