CBX7 (gene)

CBX7
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2K1B, 2L12, 2L1B, 3GS2, 4MN3, 5EPJ
Identifiers
Aliases	CBX7, chromobox 7
External IDs	OMIM: 608457; MGI: 1196439; HomoloGene: 65296; GeneCards: CBX7; OMA:CBX7 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	39,152,680 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	79,855,320 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; paraflocculus of cerebellum; ; Brodmann area 10; ; right hemisphere of cerebellum; ; frontal pole; ; gastric mucosa; ; middle frontal gyrus; ; Pons; ; right coronary artery; ; right frontal lobe;
	Top expressed in
	yolk sac; ; spermatocyte; ; neural layer of retina; ; cerebellar cortex; ; muscle of thigh; ; superior frontal gyrus; ; mesenteric lymph nodes; ; epiblast; ; lip; ; right kidney;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; methylated histone binding; chromatin binding; single-stranded RNA binding;
Cellular component	PcG protein complex; nucleus; nucleoplasm; cytosol; PRC1 complex;
Biological process	regulation of transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; chromatin organization; sebaceous gland development;
	Sources:Amigo / QuickGO
Orthologs
	23492
	52609
	ENSG00000100307
	ENSMUSG00000053411
	O95931
	Q8VDS3
	NM_175709; NM_001346743; NM_001346744
	NM_144811
	NP_001333672; NP_001333673; NP_783640; NP_783640.1
	NP_659060
	Wikidata
View/Edit Human	View/Edit Mouse

Chromobox homolog 7 is a protein that in humans is encoded by the CBX7 gene. The loss of CBX7 gene expression has been shown to correlate with a malignant form of thyroid cancer.