CCL11

CCL11
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1EOT, 2EOT, 2MPM
Identifiers
Aliases	CCL11, SCYA11, C-C motif chemokine ligand 11
External IDs	OMIM: 601156; MGI: 103576; HomoloGene: 7929; GeneCards: CCL11; OMA:CCL11 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	34,288,334 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	81,953,781 bp
RNA expression pattern
	Top expressed in
	pylorus; ; cardia; ; cecum; ; appendix; ; epithelium of colon; ; muscle layer of sigmoid colon; ; right ventricle; ; fundus; ; duodenum; ; mucosa of transverse colon;
	Top expressed in
	cervix; ; lumbar spinal ganglion; ; intercostal muscle; ; migratory enteric neural crest cell; ; sciatic nerve; ; white adipose tissue; ; muscle of thigh; ; tunica adventitia of aorta; ; lip; ; medial head of gastrocnemius muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	cytokine activity; protein binding; chemokine activity; CCR3 chemokine receptor binding; protein dimerization activity; receptor ligand activity; CCR chemokine receptor binding;
Cellular component	extracellular region; extracellular space; intracellular anatomical structure;
Biological process	G protein-coupled receptor signaling pathway; positive regulation of endothelial cell proliferation; positive regulation of actin filament polymerization; response to interleukin-4; branching involved in mammary gland duct morphogenesis; monocyte chemotaxis; actin filament organization; positive regulation of cell migration; chemokine-mediated signaling pathway; response to interleukin-13; cellular response to tumor necrosis factor; response to virus; cellular calcium ion homeostasis; mast cell chemotaxis; neutrophil chemotaxis; positive regulation of angiogenesis; mammary duct terminal end bud growth; chemotaxis; protein phosphorylation; positive regulation of GTPase activity; cell adhesion; cytoskeleton organization; cellular response to interleukin-1; immune response; positive regulation of ERK1 and ERK2 cascade; regulation of cell shape; cellular response to interferon-gamma; lymphocyte chemotaxis; response to radiation; inflammatory response; chronic inflammatory response; signal transduction; eosinophil chemotaxis; antimicrobial humoral immune response mediated by antimicrobial peptide; regulation of signaling receptor activity; cytokine-mediated signaling pathway; ERK1 and ERK2 cascade;
	Sources:Amigo / QuickGO
Orthologs
	6356
	20292
	ENSG00000172156
	ENSMUSG00000020676
	P51671
	P48298
	NM_002986
	NM_011330
	NP_002977
	NP_035460
	Wikidata
View/Edit Human	View/Edit Mouse

C-C motif chemokine 11 also known as eosinophil chemotactic protein and eotaxin-1 is a protein that in humans is encoded by the CCL11 gene. This gene is encoded on three exons and is located on chromosome 17.