CCL7

CCL7
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	1BO0, 1NCV, 4ZKC
Identifiers
Aliases	CCL7, FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7, C-C motif chemokine ligand 7
External IDs	OMIM: 158106; HomoloGene: 4568; GeneCards: CCL7; OMA:CCL7 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	34,272,242 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; mucosa of urinary bladder; ; stromal cell of endometrium; ; amniotic fluid; ; cartilage tissue; ; appendix; ; rectum; ; smooth muscle tissue; ; lower lobe of lung; ; parietal pleura;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	cytokine activity; heparin binding; chemokine activity; CCR1 chemokine receptor binding; protein binding; CCR2 chemokine receptor binding; CCR chemokine receptor binding;
Cellular component	extracellular region; extracellular space;
Biological process	G protein-coupled receptor signaling pathway; monocyte chemotaxis; positive regulation of cell migration; positive regulation of natural killer cell chemotaxis; chemokine-mediated signaling pathway; cellular response to tumor necrosis factor; cell-cell signaling; eosinophil chemotaxis; cellular calcium ion homeostasis; neutrophil chemotaxis; chemotaxis; positive regulation of GTPase activity; cytoskeleton organization; cellular response to interleukin-1; immune response; positive regulation of ERK1 and ERK2 cascade; regulation of cell shape; cellular response to interferon-gamma; inflammatory response; signal transduction; response to gamma radiation; cellular response to ethanol; regulation of signaling receptor activity; lymphocyte chemotaxis;
	Sources:Amigo / QuickGO
Orthologs
	6354
	n/a
	ENSG00000108688
	n/a
	P80098
	n/a
	NM_006273
	n/a
	NP_006264
	n/a
	Wikidata
View/Edit Human

Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine that was previously called monocyte-chemotactic protein 3 (MCP3). CCL7 is a small protein that belongs to the CC chemokine family and is most closely related to CCL2 (previously called MCP1).