Cyclin K

CCNK
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2I53, 4CXA, 4NST, 4UN0, 5EFQ, 5ACB
Identifiers
Aliases	CCNK, CPR4, Cyclin K, IDDHDF
External IDs	OMIM: 603544; MGI: 1276106; HomoloGene: 14748; GeneCards: CCNK; OMA:CCNK - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	99,535,044 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	108,169,618 bp
RNA expression pattern
	Top expressed in
	skin of arm; ; cardiac muscle tissue of right atrium; ; myocardium of left ventricle; ; mucosa of ileum; ; amniotic fluid; ; monocyte; ; tibialis anterior muscle; ; parotid gland; ; pancreatic ductal cell; ; bone marrow cells;
	Top expressed in
	zygote; ; muscle of thigh; ; tail of embryo; ; genital tubercle; ; interventricular septum; ; seminiferous tubule; ; ventricular zone; ; spermatid; ; spermatocyte; ; neural layer of retina;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; protein kinase binding; RNA polymerase II CTD heptapeptide repeat kinase activity; cyclin-dependent protein serine/threonine kinase activity; cyclin-dependent protein serine/threonine kinase regulator activity; protein serine/threonine kinase activity; cyclin-dependent protein serine/threonine kinase activator activity;
Cellular component	cyclin K-CDK12 complex; nucleus; cyclin K-CDK13 complex; nucleoplasm; cyclin-dependent protein kinase holoenzyme complex; cyclin/CDK positive transcription elongation factor complex;
Biological process	positive regulation of cyclin-dependent protein serine/threonine kinase activity; transcription elongation from RNA polymerase II promoter; regulation of cyclin-dependent protein serine/threonine kinase activity; positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues; regulation of transcription, DNA-templated; cellular response to DNA damage stimulus; transcription by RNA polymerase II; negative regulation by host of viral genome replication; positive regulation of transcription by RNA polymerase II; cell division; cell cycle; protein phosphorylation; transcription, DNA-templated; snRNA transcription by RNA polymerase II; positive regulation of phosphorylation of RNA polymerase II C-terminal domain; regulation of transcription by RNA polymerase II; positive regulation of DNA-templated transcription, elongation;
	Sources:Amigo / QuickGO
Orthologs
	8812
	12454
	ENSG00000090061
	ENSMUSG00000021258
	O75909
	O88874; Q3U3M5
	NM_001099402; NM_003858
	NM_009832
	NP_001092872
	NP_033962
	Wikidata
View/Edit Human	View/Edit Mouse

Cyclin-K is a protein that in humans is encoded by the CCNK gene.