CCRL2

CCRL2
Identifiers
Aliases	CCRL2, ACKR5, CKRX, CRAM, CRAM-A, CRAM-B, HCR, C-C motif chemokine receptor like 2
External IDs	OMIM: 608379; MGI: 1920904; HomoloGene: 2948; GeneCards: CCRL2; OMA:CCRL2 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	46,412,997 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	110,886,587 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; rectum; ; upper lobe of left lung; ; mucosa of sigmoid colon; ; appendix; ; monocyte; ; right lung; ; granulocyte; ; spleen; ; bone marrow cells;
	Top expressed in
	granulocyte; ; right lung lobe; ; embryo; ; muscle of thigh; ; stroma of bone marrow; ; triceps brachii muscle; ; vastus lateralis muscle; ; digastric muscle; ; left lung; ; temporal muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; chemokine receptor activity; signal transducer activity; CCR chemokine receptor binding; chemokine receptor binding; C-C chemokine receptor activity; chemokine binding; C-C chemokine binding;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane; cytoplasm; external side of plasma membrane;
Biological process	chemotaxis; G protein-coupled receptor signaling pathway; signal transduction; chemokine-mediated signaling pathway; inflammatory response; immune response; positive regulation of cytosolic calcium ion concentration; calcium-mediated signaling; cell chemotaxis;
	Sources:Amigo / QuickGO
Orthologs
	9034
	54199
	ENSG00000121797
	ENSMUSG00000043953
	O00421
	O35457
	NM_001130910; NM_003965
	NM_017466; NM_001302376; NM_001302377
	NP_001124382; NP_003956
	NP_001289305; NP_001289306; NP_059494
	Wikidata
View/Edit Human	View/Edit Mouse

C-C chemokine receptor-like 2 is a protein that in humans is encoded by the CCRL2 gene. Recently it was found that CCRL2 also acts as a receptor for the chemokine chemerin.