Nectin-3

NECTIN3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4FOM
Identifiers
Aliases	NECTIN3, CD113, CDW113, NECTIN-3, PPR3, PRR3, PVRR3, PVRL3, nectin cell adhesion molecule 3
External IDs	OMIM: 607147; MGI: 1930171; HomoloGene: 9162; GeneCards: NECTIN3; OMA:NECTIN3 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	111,275,563 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	46,318,888 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; sperm; ; Achilles tendon; ; islet of Langerhans; ; placenta; ; left testis; ; rectum; ; right testis; ; jejunal mucosa; ; duodenum;
	Top expressed in
	seminiferous tubule; ; spermatid; ; spermatocyte; ; ciliary body; ; iris; ; epithelium of lens; ; lumbar spinal ganglion; ; left lung lobe; ; molar; ; right lung lobe;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein homodimerization activity; protein binding; signaling receptor binding; cell adhesion molecule binding; identical protein binding; signaling receptor activity;
Cellular component	integral component of membrane; postsynaptic membrane; membrane; cell-cell junction; plasma membrane; synapse; integral component of plasma membrane; cell junction; apical junction complex; cell-cell contact zone; hippocampal mossy fiber to CA3 synapse; integral component of postsynaptic density membrane; axon; dendrite;
Biological process	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; cell recognition; retina morphogenesis in camera-type eye; cell adhesion; lens morphogenesis in camera-type eye; fertilization; adherens junction organization; homophilic cell adhesion via plasma membrane adhesion molecules; spermatid development; protein localization to cell junction; cell-cell adhesion; establishment of protein localization to plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	25945
	58998
	ENSG00000177707
	ENSMUSG00000022656
	Q9NQS3
	Q9JLB9
	NM_001243286; NM_001243288; NM_015480
	NM_021495; NM_021496; NM_021497
	NP_001230215; NP_001230217; NP_056295
	NP_067470; NP_067471; NP_067472
	Wikidata
View/Edit Human	View/Edit Mouse

Nectin-3, also known as nectin cell adhesion molecule 3, is a protein that in humans is encoded by the NECTIN3 gene.

Nectin-3 belongs to the family of immunoglobulin(Ig)-like cellular adhesion molecules involved in Ca²⁺-independent cellular adhesion in several tissues during the development and was firstly isolated at the turn of 20th and 21st century.