BMPR1A

BMPR1A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3QB4, 1ES7, 1REW, 2GOO, 2H62, 2H64, 2K3G, 2QJ9, 2QJA, 2QJB, 3NH7
Identifiers
Aliases	BMPR1A, 10q23del, ACVRLK3, ALK3, CD292, SKR5, bone morphogenetic protein receptor type 1A
External IDs	OMIM: 601299; MGI: 1338938; HomoloGene: 20911; GeneCards: BMPR1A; OMA:BMPR1A - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	86,932,825 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	34,225,298 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; Achilles tendon; ; saphenous vein; ; parotid gland; ; tail of epididymis; ; biceps brachii; ; seminal vesicula; ; popliteal artery; ; tibial arteries; ; urethra;
	Top expressed in
	ascending aorta; ; aortic valve; ; vas deferens; ; vestibular sensory epithelium; ; efferent ductule; ; genital tubercle; ; calvaria; ; epithelium of lens; ; iris; ; vestibular membrane of cochlear duct;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; protein homodimerization activity; metal ion binding; kinase activity; protein serine/threonine kinase activity; transmembrane receptor protein serine/threonine kinase activity; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific; SMAD binding; ATP binding; BMP receptor activity; transforming growth factor beta-activated receptor activity; transforming growth factor beta receptor activity, type I; growth factor binding;
Cellular component	integral component of membrane; HFE-transferrin receptor complex; membrane; plasma membrane; soma; dendrite; caveola; external side of plasma membrane; integral component of plasma membrane; receptor complex; cell surface;
Biological process	somitogenesis; pattern specification process; roof of mouth development; cell differentiation; pituitary gland development; endoderm development; chondrocyte differentiation; neural crest cell development; lateral mesoderm development; lung development; positive regulation of bone mineralization; embryonic organ development; paraxial mesoderm structural organization; positive regulation of epithelial cell proliferation; phosphorylation; negative regulation of neurogenesis; positive regulation of pathway-restricted SMAD protein phosphorylation; mesoderm formation; ectoderm development; embryonic digit morphogenesis; heart morphogenesis; cellular response to BMP stimulus; in utero embryonic development; BMP signaling pathway; hindlimb morphogenesis; nervous system development; dorsal/ventral axis specification; regulation of lateral mesodermal cell fate specification; stem cell population maintenance; odontogenesis of dentin-containing tooth; Mullerian duct regression; endocardial cushion formation; protein phosphorylation; positive regulation of transcription, DNA-templated; heart development; cartilage development; positive regulation of osteoblast differentiation; developmental growth; transmembrane receptor protein serine/threonine kinase signaling pathway; positive regulation of mesenchymal cell proliferation; heart formation; neural plate pattern specification; embryonic morphogenesis; mesendoderm development; immune response; regulation of cellular senescence; neural plate mediolateral regionalization; dorsal/ventral pattern formation; transforming growth factor beta receptor signaling pathway; positive regulation of SMAD protein signal transduction; anterior/posterior pattern specification; paraxial mesoderm development; positive regulation of pri-miRNA transcription by RNA polymerase II; negative regulation of smooth muscle cell migration; BMP signaling pathway involved in heart development; regulation of cardiac muscle cell apoptotic process; outflow tract septum morphogenesis; outflow tract morphogenesis; cardiac conduction system development; mitral valve morphogenesis; tricuspid valve morphogenesis; endocardial cushion morphogenesis; cardiac right ventricle morphogenesis; ventricular trabecula myocardium morphogenesis; ventricular compact myocardium morphogenesis; dorsal aorta morphogenesis; positive regulation of transcription by RNA polymerase II; regulation of cardiac muscle cell proliferation; positive regulation of cardiac muscle cell proliferation; pharyngeal arch artery morphogenesis; positive regulation of cardiac ventricle development; positive regulation of vascular associated smooth muscle cell proliferation; fibrous ring of heart morphogenesis; regulation of neural crest cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	657
	12166
	ENSG00000107779
	ENSMUSG00000021796
	P36894
	P36895
	NM_004329
	NM_009758
	NP_004320
	NP_033888
	Wikidata
View/Edit Human	View/Edit Mouse

The bone morphogenetic protein receptor, type IA also known as BMPR1A is a protein which in humans is encoded by the BMPR1A gene. BMPR1A has also been designated as CD292 (cluster of differentiation 292).