CD5L

CD5L
Identifiers
Aliases	CD5L, AIM, API6, PRO229, SP-ALPHA, Spalpha, CT-2, hAIM, CD5 molecule like
External IDs	OMIM: 602592; MGI: 1334419; HomoloGene: 55936; GeneCards: CD5L; OMA:CD5L - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	157,898,256 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	87,278,380 bp
RNA expression pattern
	Top expressed in
	spleen; ; trabecular bone; ; liver; ; testicle; ; right lobe of liver; ; buccal mucosa cell; ; lymph node; ; bone marrow; ; bone marrow cells; ; placenta;
	Top expressed in
	stroma of bone marrow; ; fetal liver hematopoietic progenitor cell; ; mesenteric lymph nodes; ; left lobe of liver; ; spleen; ; calvaria; ; tibiofemoral joint; ; granulocyte; ; human fetus; ; subcutaneous adipose tissue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	scavenger receptor activity;
Cellular component	cytoplasm; extracellular region; extracellular exosome; blood microparticle; membrane; extracellular space; plasma membrane; cell surface;
Biological process	cellular defense response; inflammatory response; receptor-mediated endocytosis; immune system process; apoptotic process; vesicle-mediated transport; regulation of complement activation; positive regulation of complement-dependent cytotoxicity; endocytosis;
	Sources:Amigo / QuickGO
Orthologs
	922
	11801
	ENSG00000073754
	ENSMUSG00000015854
	O43866
	Q9QWK4
	NM_005894; NM_001347698
	NM_009690
	NP_001334627; NP_005885
	NP_033820
	Wikidata
View/Edit Human	View/Edit Mouse

CD5 antigen-like is a protein (also known as AIM, for apoptosis inhibitor of macrophage) that in humans is encoded by the CD5L gene. It is expressed by macrophages. It regulates immune responses and inflammation. It plays a crucial role in key intracellular processes like lipid metabolism and apoptosis.