CD63

CD63
Identifiers
Aliases	CD63, LAMP-3, ME491, MLA1, OMA81H, TSPAN30, CD63 molecule
External IDs	OMIM: 155740; MGI: 99529; HomoloGene: 37526; GeneCards: CD63; OMA:CD63 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	55,729,707 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	128,748,691 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; tendon of biceps brachii; ; beta cell; ; lower lobe of lung; ; upper lobe of lung; ; left adrenal gland; ; olfactory bulb; ; Descending thoracic aorta; ; upper lobe of left lung; ; decidua;
	Top expressed in
	right kidney; ; proximal tubule; ; human kidney; ; islet of Langerhans; ; morula; ; blastocyst; ; yolk sac; ; stomach; ; urinary bladder; ; adrenal gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	integral component of membrane; multivesicular body; endosome; multivesicular body membrane; membrane; late endosome membrane; intrinsic component of plasma membrane; melanosome; plasma membrane; integral component of plasma membrane; endosome lumen; multivesicular body, internal vesicle; lysosomal membrane; extracellular region; platelet dense granule membrane; lysosome; endosome membrane; extracellular exosome; extracellular space; cell surface; azurophil granule membrane; late endosome;
Biological process	positive regulation of receptor internalization; platelet degranulation; pigment granule maturation; endosome to melanosome transport; protein transport; positive regulation of integrin-mediated signaling pathway; cell-matrix adhesion; cell migration; neutrophil degranulation; transport; pigmentation; pigment cell differentiation; regulation of vascular endothelial growth factor signaling pathway; cell surface receptor signaling pathway; positive regulation of endocytosis; regulation of potassium ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	967
	12512
	ENSG00000135404
	ENSMUSG00000025351
	P08962
	P41731
NM_001780; NM_001040034; NM_001257389; NM_001257390; NM_001257391;
	NM_001257392; NM_001257400; NM_001257401; NM_001267698
	NM_001042580; NM_001282966; NM_007653
NP_001244318; NP_001244319; NP_001244320; NP_001244321; NP_001244329;
	NP_001244330; NP_001254627; NP_001771
	NP_001036045; NP_001269895; NP_031679
	Wikidata
View/Edit Human	View/Edit Mouse

CD63 antigen is a protein that, in humans, is encoded by the CD63 gene. CD63 is mainly associated with membranes of intracellular vesicles, although cell surface expression may be induced.