CEACAM3

CEACAM3
Identifiers
Aliases	CEACAM3, CD66D, CEA, CGM1, W264, W282, carcinoembryonic antigen related cell adhesion molecule 3, CEA cell adhesion molecule 3
External IDs	OMIM: 609142; HomoloGene: 130497; GeneCards: CEACAM3; OMA:CEACAM3 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	41,811,554 bp
RNA expression pattern
	Top expressed in
	blood; ; granulocyte; ; bone marrow; ; bone marrow cells; ; periodontal fiber; ; monocyte; ; spleen; ; mucosa of transverse colon; ; trabecular bone; ; cecum;
	n/a
	More reference expression data
	; ;
	More reference expression data
Orthologs
	1084
	n/a
	ENSG00000170956
	n/a
	P40198
	n/a
	NM_001277163; NM_001815
	n/a
	NP_001264092; NP_001806
	n/a
	Wikidata
View/Edit Human

Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) also known as CD66d (Cluster of Differentiation 66d), is a member of the carcinoembryonic antigen (CEA) gene family..

This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.