CD79A

CD79A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCD79A, IGA, MB-1, CD79a molecule, MB1, IGAlpha
External IDsOMIM: 112205; MGI: 101774; HomoloGene: 31053; GeneCards: CD79A; OMA:CD79A - orthologs
Orthologs
SpeciesHumanMouse
Entrez

973

12518

Ensembl

ENSG00000105369

ENSMUSG00000003379

UniProt

P11912

P11911

RefSeq (mRNA)

NM_021601
NM_001783

NM_007655

RefSeq (protein)

NP_001774
NP_067612

NP_031681

Location (UCSC)Chr 19: 41.88 – 41.88 MbChr 7: 24.6 – 24.6 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Cluster of differentiation CD79A also known as B-cell antigen receptor complex-associated protein alpha chain and MB-1 membrane glycoprotein, is a protein that in humans is encoded by the CD79A gene.

The CD79a protein together with the related CD79b protein, forms a dimer associated with membrane-bound immunoglobulin in B-cells, thus forming the B-cell antigen receptor (BCR). This occurs in a similar manner to the association of CD3 with the T-cell receptor, and enables the cell to respond to the presence of antigens on its surface.

It is associated with agammaglobulinemia-3.