CDCA7

CDCA7
Identifiers
AliasesCDCA7, JPO1, ICF3, cell division cycle associated 7
External IDsOMIM: 609937; MGI: 1914203; HomoloGene: 49970; GeneCards: CDCA7; OMA:CDCA7 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

83879

66953

Ensembl

ENSG00000144354

ENSMUSG00000055612

UniProt

Q9BWT1

Q9D0M2

RefSeq (mRNA)

NM_031942
NM_145810

NM_025866

RefSeq (protein)

NP_114148
NP_665809

NP_080142

Location (UCSC)Chr 2: 173.35 – 173.37 MbChr 2: 72.31 – 72.32 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Cell division cycle-associated protein 7 is a protein that in humans is encoded by the CDCA7 gene.

This gene was identified as a c-Myc responsive gene, and behaves as a direct c-Myc target gene. Overexpression of this gene is found to enhance the transformation of lymphoblastoid cells, and it complements a transformation-defective Myc Box II mutant, suggesting its involvement in c-Myc-mediated cell transformation. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.