Cadherin related family member 3

CDHR3
Identifiers
Aliases	CDHR3, CDH28, cadherin related family member 3
External IDs	OMIM: 615610; MGI: 1916014; HomoloGene: 45146; GeneCards: CDHR3; OMA:CDHR3 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	106,036,432 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	33,142,874 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; bronchial epithelial cell; ; olfactory zone of nasal mucosa; ; mucosa of paranasal sinus; ; right lung; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; epithelium of nasopharynx; ; gastric mucosa; ; muscle layer of sigmoid colon;
	Top expressed in
	olfactory epithelium; ; right lung lobe; ; left lung lobe; ; Epithelium of choroid plexus; ; aorta; ; esophagus; ; paraventricular nucleus of hypothalamus; ; dentate gyrus; ; dentate gyrus of hippocampal formation granule cell; ; habenula;
	More reference expression data
	n/a
Gene ontology
Molecular function	calcium ion binding; virus receptor activity; cytoskeletal protein binding; protein homodimerization activity; cadherin binding;
Cellular component	integral component of membrane; plasma membrane; membrane; cell surface; catenin complex;
Biological process	viral entry into host cell; cell adhesion; viral process; homophilic cell adhesion via plasma membrane adhesion molecules; cell-cell junction assembly; calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; adherens junction organization; cell-cell adhesion mediated by cadherin; cell-cell adhesion; cell morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	222256
	68764
	ENSG00000128536
	ENSMUSG00000035860
	Q6ZTQ4
	Q8BL00
	NM_001301161; NM_152750
	NM_001024478
	NP_001288090; NP_689963
	NP_001019649
	Wikidata
View/Edit Human	View/Edit Mouse

Cadherin related family member 3 (CDHR3), also known as CDH28 or its abbreviation CDHR3, is a protein that in humans is encoded by the CDHR3 gene. The protein is predominately expressed in respiratory epithelium and the first notion of its clinical implications was from the discovery that genetic variation of CDHR3 is strongly associated to early severe asthma exacerbations in children. Subsequent studies have suggested that CDHR3 is a receptor for a subtype of rhinovirus.