CDKL2

CDKL2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4AAA, 4BBM
Identifiers
Aliases	CDKL2, KKIAMRE, P56, cyclin dependent kinase like 2
External IDs	OMIM: 603442; MGI: 1858227; HomoloGene: 55793; GeneCards: CDKL2; OMA:CDKL2 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	75,630,716 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	92,043,883 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; Brodmann area 23; ; middle temporal gyrus; ; postcentral gyrus; ; superior frontal gyrus; ; testicle; ; primary visual cortex; ; entorhinal cortex; ; lower lobe of lung; ; prefrontal cortex;
	Top expressed in
	barrel cortex; ; lumbar spinal ganglion; ; spermatocyte; ; facial motor nucleus; ; seminiferous tubule; ; olfactory epithelium; ; spermatid; ; vestibular sensory epithelium; ; zygote; ; Epithelium of choroid plexus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; protein kinase activity; nucleotide binding; protein serine/threonine kinase activity; ATP binding; kinase activity; cyclin-dependent protein serine/threonine kinase activity;
Cellular component	cytoplasm; centrosome; nucleus;
Biological process	protein phosphorylation; sex differentiation; phosphorylation; signal transduction; regulation of cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	8999
	53886
	ENSG00000138769
	ENSMUSG00000029403
	Q92772
	Q9QUK0
	NM_003948; NM_001330724
	NM_001276315; NM_016912; NM_177270
	NP_001317653; NP_003939
	NP_001263244; NP_058608; NP_796244
	Wikidata
View/Edit Human	View/Edit Mouse

Cyclin-dependent kinase-like 2 is an enzyme that in humans is encoded by the CDKL2 gene.

This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus.