CDw17 antigen

CDw17 antigen is a lactosylceramide, a class of glycosphingolipids found in microdomains on the plasma layers of numerous cells. It is found on human neutrophils, basophils, monocyte, platelets, tonsillar CD45+ dendritic cells, epithelial cells, endothelial cells in intestinal epithelium, and on post-proliferative granulocytes in the bone marrow.

CDw17 acts as a precursor for biosynthesis of glycosphingolipids.

The enzyme A4GALT acts upon it, aiding transfer of galactose to lactosylceramide to form globotriaosylceramide.

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