CENPC1

CENPC
Identifiers
Aliases	CENPC, CENP-C, CENPC1, MIF2, hcp-4, centromere protein C
External IDs	OMIM: 117141; MGI: 99700; HomoloGene: 1371; GeneCards: CENPC; OMA:CENPC - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	67,545,503 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	86,213,442 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; sural nerve; ; corpus callosum; ; bone marrow cells; ; testicle; ; tonsil; ; body of pancreas; ; gonad; ; ventricular zone; ; lymph node;
	Top expressed in
	spermatocyte; ; tail of embryo; ; genital tubercle; ; ventricular zone; ; Gonadal ridge; ; otic placode; ; superior cervical ganglion; ; abdominal wall; ; otic vesicle; ; saccule;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; centromeric DNA binding; protein binding; identical protein binding;
Cellular component	pericentric heterochromatin; chromosome; chromosome, centromeric region; kinetochore; nucleus; nucleoplasm; cytosol; nuclear body; midbody; cleavage furrow; intercellular bridge; Flemming body;
Biological process	chromosome segregation; cell division; kinetochore assembly; cell cycle; CENP-A containing chromatin assembly; attachment of mitotic spindle microtubules to kinetochore; monopolar spindle attachment to meiosis I kinetochore; mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	1060
	12617
	ENSG00000145241
	ENSMUSG00000029253
	Q03188
	P49452
	NM_001812; NM_001362481
	NM_007683; NM_001345902; NM_001345903; NM_001345904
	NP_001803; NP_001349410
	NP_001332831; NP_001332832; NP_001332833; NP_031709
	Wikidata
View/Edit Human	View/Edit Mouse

Centromere protein C 1 is a protein that in humans is encoded by the CENPC1 gene.

Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore size and a timely transition to anaphase. A putative pseudogene exists on chromosome 12.