CENPF

CENPF
Identifiers
Aliases	CENPF, CENF, PRO1779, hcp-1, CILD31, STROMS, centromere protein F
External IDs	OMIM: 600236; MGI: 1313302; HomoloGene: 22969; GeneCards: CENPF; OMA:CENPF - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	214,664,571 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	189,420,283 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; gonad; ; testicle; ; trabecular bone; ; stromal cell of endometrium; ; bone marrow; ; bone marrow cells; ; mucosa of transverse colon; ; left testis;
	Top expressed in
	zygote; ; primary oocyte; ; tail of embryo; ; genital tubercle; ; maxillary prominence; ; ventricular zone; ; secondary oocyte; ; fetal liver hematopoietic progenitor cell; ; superior cervical ganglion; ; mandibular prominence;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein homodimerization activity; transcription factor binding; chromatin binding; protein C-terminus binding; protein binding; dynein complex binding;
Cellular component	cytoplasm; ciliary basal body; cytosol; centrosome; spindle pole; nuclear envelope; nuclear matrix; spindle; nucleoplasm; ciliary transition fiber; chromosome; midbody; outer kinetochore; perinuclear region of cytoplasm; pronucleus; axoneme; chromatin; chromosome, centromeric region; cytoskeleton; nucleus; kinetochore;
Biological process	regulation of G2/M transition of mitotic cell cycle; regulation of striated muscle tissue development; cell differentiation; metaphase plate congression; DNA biosynthetic process; kidney development; chromosome segregation; muscle organ development; ventricular system development; mitotic spindle assembly checkpoint signaling; regulation of cell cycle; cell division; multicellular organism development; protein transport; cell cycle; cell population proliferation; negative regulation of transcription, DNA-templated; kinetochore assembly; mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	1063
	108000
	ENSG00000117724
	ENSMUSG00000026605
	P49454
	n/a
	NM_016343
	NM_001081363
	NP_057427
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Centromere protein F is a protein that in humans is encoded by the CENPF gene. It is involved in chromosome segregation during cell division. It also has a role in the orientation of microtubules to form cellular cilia.