CEP57

CEP57
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4L0R
Identifiers
Aliases	CEP57, MVA2, PIG8, TSP57, centrosomal protein 57
External IDs	OMIM: 607951; MGI: 1915551; HomoloGene: 8790; GeneCards: CEP57; OMA:CEP57 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	95,832,693 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	13,738,403 bp
RNA expression pattern
	Top expressed in
	oocyte; ; Achilles tendon; ; sperm; ; ganglionic eminence; ; secondary oocyte; ; gallbladder; ; hair follicle; ; ventricular zone; ; Epithelium of choroid plexus; ; cartilage tissue;
	Top expressed in
	seminiferous tubule; ; hand; ; spermatid; ; genital tubercle; ; tail of embryo; ; spermatocyte; ; ventricular zone; ; epiblast; ; abdominal wall; ; thymus;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein homodimerization activity; microtubule binding; protein binding; identical protein binding; fibroblast growth factor binding; gamma-tubulin binding;
Cellular component	cytosol; centrosome; Golgi apparatus; microtubule organizing center; microtubule; cytoskeleton; nucleus; cytoplasm; microtubule cytoskeleton; nucleoplasm;
Biological process	fibroblast growth factor receptor signaling pathway; microtubule anchoring; G2/M transition of mitotic cell cycle; spermatid development; mitotic sister chromatid segregation; protein homooligomerization; ciliary basal body-plasma membrane docking; regulation of G2/M transition of mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	9702
	74360
	ENSG00000166037
	ENSMUSG00000031922
	Q86XR8
	Q8CEE0
	NM_001243776; NM_001243777; NM_014679; NM_001363604
	NM_026665; NM_001310721
	NP_001230705; NP_001230706; NP_055494; NP_001350533
	NP_001297650; NP_080941
	Wikidata
View/Edit Human	View/Edit Mouse

Centrosomal protein of 57 kDa is a protein that in humans is encoded by the CEP57 gene. It is also known as translokin.

Translokin binds basic fibroblast growth factor (FGF2; MIM 134920) and mediates its nuclear translocation and mitogenic activity (Bossard et al., 2003).[supplied by OMIM]