CFAP157

CFAP157
Identifiers
Aliases	CFAP157, C9orf117, cilia and flagella associated protein 157
External IDs	MGI: 2447809; HomoloGene: 53056; GeneCards: CFAP157; OMA:CFAP157 - orthologs
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	32,674,440 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; bronchial epithelial cell; ; left uterine tube; ; sperm; ; right lung; ; anterior pituitary; ; canal of the cervix; ; trachea; ; pancreatic ductal cell; ; upper lobe of left lung;
	Top expressed in
	spermatid; ; seminiferous tubule; ; lip; ; spermatocyte; ; neural layer of retina; ; morula; ; pharynx; ; embryo; ; nasopharynx; ; epithelium of trachea;
	More reference expression data
	n/a
Gene ontology
Molecular function	microtubule binding;
Cellular component	cytosol; plasma membrane; cilium; cell projection; intracellular membrane-bounded organelle; ciliary basal body; cytoplasm; cytoskeleton;
Biological process	sperm axoneme assembly; spermatogenesis; cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	286207
	227736
	n/a
	ENSMUSG00000038987
	Q5JU67
	Q0VFX2
	NM_001012502
	NM_025619
	NP_001012520
	NP_079895
	Wikidata
View/Edit Human	View/Edit Mouse

Cilia and flagella associated protein 157 (CFAP157) also known as chromosome 9 open reading frame 117 (c9orf117) is a protein that in humans is encoded by the CFAP157 gene.

CFAP157 gene is "specifically required during spermatogenesis for flagellum morphogenesis and sperm motility and may be required to suppress the formation of supernumerary axonemes and ensure a correct ultrastructure," according to UniProt.