CFP-10
| 10 kDa culture filtrate antigen CFP-10 | |||||||
|---|---|---|---|---|---|---|---|
Structure of the CFP10-ESAT6 complex from M. tuberculosis. | |||||||
| Identifiers | |||||||
| Organism | |||||||
| Symbol | esxB | ||||||
| Entrez | 886194 | ||||||
| PDB | 3FAV | ||||||
| RefSeq (Prot) | NP_218391 | ||||||
| UniProt | P0A566 | ||||||
| Other data | |||||||
| Chromosome | genome: 4.35 - 4.35 Mb | ||||||
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CFP-10 within bacterial proteins (also known as ESAT-6-like protein esxB or secreted antigenic protein MTSA-10 or 10 kDa culture filtrate antigen CFP-10) is a protein that is encoded by the esxB gene.
CFP-10 is a 10 kDa secreted antigen from Mycobacterium tuberculosis. It forms a 1:1 heterodimeric complex with ESAT-6. Both genes are expressed from the RD1 region of the bacterial genome and play a key role in the virulence of the infection.