Chimerin 1
| chimerin (chimaerin) 1 | |||||||
|---|---|---|---|---|---|---|---|
Crystal structure of human chimerin 1 (CHN1) | |||||||
| Identifiers | |||||||
| Symbol | CHN1 | ||||||
| Alt. symbols | CHN | ||||||
| NCBI gene | 1123 | ||||||
| HGNC | 1943 | ||||||
| OMIM | 118423 | ||||||
| RefSeq | NM_001822 | ||||||
| UniProt | P15882 | ||||||
| Other data | |||||||
| Locus | Chr. 2 q31-q32.1 | ||||||
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Chimerin 1 (CHN1), also known as alpha-1-chimerin, n-chimerin, is a protein which in humans is encoded by the CHN1 gene.
Chimerin 1 is a GTPase activating protein specific for RAC GTP-binding proteins. It is expressed primarily in the brain and may be involved in signal transduction.
This gene encodes GTPase-activating protein for p21-rac and a phorbol ester receptor. It plays an important role in ocular motor axon pathfinding.