Muscarinic acetylcholine receptor M4

CHRM4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5DSG
Identifiers
Aliases	CHRM4, HM4, M4R, cholinergic receptor muscarinic 4
External IDs	OMIM: 118495; MGI: 88399; HomoloGene: 20192; GeneCards: CHRM4; OMA:CHRM4 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	46,391,776 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	91,759,033 bp
RNA expression pattern
	Top expressed in
	testicle; ; caudate nucleus; ; putamen; ; nucleus accumbens; ; right frontal lobe; ; spleen; ; prefrontal cortex; ; anterior cingulate cortex; ; Brodmann area 9; ; left testis;
	Top expressed in
	superior frontal gyrus; ; primary visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; embryo; ; pretectal area; ; embryo; ; spermatid; ; secondary oocyte; ; zygote; ; meninges;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; G protein-coupled acetylcholine receptor activity; G protein-coupled serotonin receptor activity; neurotransmitter receptor activity;
Cellular component	integral component of membrane; postsynaptic membrane; membrane; plasma membrane; synapse; integral component of plasma membrane; cell junction; dendrite;
Biological process	G protein-coupled acetylcholine receptor signaling pathway; regulation of locomotion; synaptic transmission, cholinergic; cell surface receptor signaling pathway; adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway; phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway; cell population proliferation; signal transduction; G protein-coupled receptor signaling pathway; G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; chemical synaptic transmission; G protein-coupled serotonin receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	1132
	12672
	ENSG00000180720
	ENSMUSG00000040495
	P08173
	P32211
	NM_000741; NM_001366692
	NM_007699
	NP_000732; NP_001353621
	NP_031725
	Wikidata
View/Edit Human	View/Edit Mouse

The muscarinic acetylcholine receptor M₄, also known as the cholinergic receptor, muscarinic 4 (CHRM4), is a protein that, in humans, is encoded by the CHRM4 gene.