CKAP4

CKAP4
Identifiers
Aliases	CKAP4, CLIMP-63, ERGIC-63, p63, cytoskeleton-associated protein 4, cytoskeleton associated protein 4, CLIMP63
External IDs	MGI: 2444926; HomoloGene: 4970; GeneCards: CKAP4; OMA:CKAP4 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	106,304,279 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	84,369,926 bp
RNA expression pattern
	Top expressed in
	tibia; ; gingival epithelium; ; stromal cell of endometrium; ; cartilage tissue; ; buccal mucosa cell; ; periodontal fiber; ; pancreatic ductal cell; ; parietal pleura; ; germinal epithelium; ; mucosa of sigmoid colon;
	Top expressed in
	ascending aorta; ; calvaria; ; fossa; ; aortic valve; ; condyle; ; granulocyte; ; tibiofemoral joint; ; body of femur; ; Rostral migratory stream; ; decidua;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	RNA binding;
Cellular component	cytoplasm; perinuclear region of cytoplasm; integral component of membrane; lipid droplet; plasma membrane; lamellar granule; extracellular exosome; cytoskeleton; endoplasmic reticulum membrane; endoplasmic reticulum; membrane; extracellular matrix; cytosol; nuclear speck; azurophil granule membrane; specific granule membrane; endoplasmic reticulum lumen; rough endoplasmic reticulum; cytoplasmic ribonucleoprotein granule;
Biological process	neutrophil degranulation; post-translational protein modification;
	Sources:Amigo / QuickGO
Orthologs
	10970
	216197
	ENSG00000136026
	ENSMUSG00000046841
	Q07065
	Q8BMK4
	NM_006825
	NM_175451
	NP_006816
	NP_780660
	Wikidata
View/Edit Human	View/Edit Mouse

Cytoskeleton-associated protein 4 is a protein that in humans is encoded by the CKAP4 gene.

CKAP4 also historically known as CLIMP-63 (cytoskeleton-linking membrane protein 63), or just p63 (during the 1990s) is an abundant type II transmembrane protein residing predominantly in the endoplasmic reticulum (ER) of eukaryotic cells and encoded in higher vertebrates by the gene CKAP4.