CKMT1A
| creatine kinase, mitochondrial 1A | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | CKMT1A | ||||||
| Alt. symbols | CKMT1 | ||||||
| NCBI gene | 548596 | ||||||
| HGNC | 31736 | ||||||
| RefSeq | NM_001015001 | ||||||
| UniProt | P12532 | ||||||
| Other data | |||||||
| EC number | 2.7.3.2 | ||||||
| Locus | Chr. 15 q15 | ||||||
| |||||||
Creatine kinase U-type, mitochondrial, also called ubiquitous mitochondrial creatine kinase (uMtCK), is in humans encoded by CKMT1A gene. CKMT1A catalyzes the reversible transfer of the γ-phosphate group of ATP to the guanidino group of Cr to yield ADP and PCr. The impairment of CKMT1A has been reported in ischaemia, cardiomyopathy, and neurodegenerative disorders. Overexpression of CKMT1A has been reported related with several tumors.