CLDN1

CLDN1
Identifiers
Aliases	CLDN1, CLD1, ILVASC, SEMP1, claudin 1
External IDs	OMIM: 603718; MGI: 1276109; HomoloGene: 9620; GeneCards: CLDN1; OMA:CLDN1 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	190,322,446 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	26,190,591 bp
RNA expression pattern
	Top expressed in
	skin of thigh; ; germinal epithelium; ; skin of hip; ; skin of abdomen; ; olfactory zone of nasal mucosa; ; epithelium of nasopharynx; ; left uterine tube; ; right lobe of liver; ; nipple; ; gingival epithelium;
	Top expressed in
	retinal pigment epithelium; ; decidua; ; molar; ; skin of external ear; ; lip; ; Epithelium of choroid plexus; ; epidermis; ; hair follicle; ; skin of abdomen; ; lumbar spinal ganglion;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; structural molecule activity; identical protein binding; virus receptor activity;
Cellular component	membrane; integral component of membrane; cell junction; plasma membrane; integral component of plasma membrane; apical plasma membrane; lateral plasma membrane; bicellular tight junction; cytoplasm; basolateral plasma membrane;
Biological process	viral entry into host cell; cell-cell junction organization; calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; viral process; protein homooligomerization; protein heterooligomerization; establishment of skin barrier; bicellular tight junction assembly; ageing; establishment of blood-nerve barrier; response to toxic substance; response to lipopolysaccharide; hyperosmotic salinity response; response to ethanol; xenobiotic transport across blood-nerve barrier; response to interleukin-18; cellular response to lead ion; cellular response to interferon-gamma; cellular response to tumor necrosis factor; response to dexamethasone; cellular response to transforming growth factor beta stimulus; establishment of endothelial intestinal barrier; liver regeneration; positive regulation of bicellular tight junction assembly; cellular response to butyrate;
	Sources:Amigo / QuickGO
Orthologs
	9076
	12737
	ENSG00000163347
	ENSMUSG00000022512
	O95832
	O88551
	NM_021101
	NM_016674
	NP_066924
	NP_057883
	Wikidata
View/Edit Human	View/Edit Mouse

Claudin-1 is a protein that in humans is encoded by the CLDN1 gene. It belongs to the group of claudins.