CLDN11

CLDN11
Identifiers
Aliases	CLDN11, OSP, OTM, claudin 11, HLD22
External IDs	OMIM: 601326; MGI: 106925; HomoloGene: 4093; GeneCards: CLDN11; OMA:CLDN11 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	170,454,733 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	31,218,473 bp
RNA expression pattern
	Top expressed in
	inferior ganglion of vagus nerve; ; subthalamic nucleus; ; superior vestibular nucleus; ; ventral tegmental area; ; Pons; ; external globus pallidus; ; pars reticulata; ; C1 segment; ; trigeminal ganglion; ; pars compacta;
	Top expressed in
	ventral tegmental area; ; lateral geniculate nucleus; ; globus pallidus; ; stria vascularis; ; deep cerebellar nuclei; ; pontine nuclei; ; pineal gland; ; lateral hypothalamus; ; medial geniculate nucleus; ; lumbar subsegment of spinal cord;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	structural molecule activity; identical protein binding; protein binding;
Cellular component	integral component of membrane; cell junction; membrane; bicellular tight junction; plasma membrane;
Biological process	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;
	Sources:Amigo / QuickGO
Orthologs
	5010
	18417
	ENSG00000013297
	ENSMUSG00000037625
	O75508
	Q60771
	NM_005602; NM_001185056
	NM_008770
	NP_001171985; NP_005593
	NP_032796
	Wikidata
View/Edit Human	View/Edit Mouse

Claudin-11 is a protein that in humans is encoded by the CLDN11 gene. It belongs to the group of claudins and was the first member of the family to be knocked out in mice, thereby demonstrating the central role of claudins for intramembranous strands observed in freeze-fracture images.