CLDN2

CLDN2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4YYX
Identifiers
Aliases	CLDN2, claudin 2, OAZON
External IDs	OMIM: 300520; MGI: 1276110; HomoloGene: 9621; GeneCards: CLDN2; OMA:CLDN2 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	106,930,861 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	138,712,135 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; gallbladder; ; islet of Langerhans; ; right lobe of liver; ; seminal vesicula; ; renal cortex; ; renal medulla; ; duodenum; ; caput epididymis; ; human kidney;
	Top expressed in
	Epithelium of choroid plexus; ; human kidney; ; proximal tubule; ; right kidney; ; choroid plexus of fourth ventricle; ; crypt of lieberkuhn of small intestine; ; efferent ductule; ; left colon; ; yolk sac; ; left lobe of liver;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; identical protein binding; structural molecule activity;
Cellular component	cell junction; integral component of membrane; bicellular tight junction; plasma membrane; membrane;
Biological process	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules;
	Sources:Amigo / QuickGO
Orthologs
	9075
	12738
	ENSG00000165376
	ENSMUSG00000047230
	P57739
	O88552
	NM_020384; NM_001171092; NM_001171095
	NM_016675
	NP_001164563; NP_001164566; NP_065117
	NP_057884
	Wikidata
View/Edit Human	View/Edit Mouse

Claudin-2 is a protein that in humans is encoded by the CLDN2 gene. It belongs to the group of claudins.

Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions (Sakaguchi et al., 2002).[supplied by OMIM]