| CLIP2 |
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| Identifiers |
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| Aliases | CLIP2, CLIP, CLIP-115, CYLN2, WBSCR3, WBSCR4, WSCR3, WSCR4, CAP-Gly domain containing linker protein 2 |
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| External IDs | OMIM: 603432; MGI: 1313136; HomoloGene: 20718; GeneCards: CLIP2; OMA:CLIP2 - orthologs |
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| Gene location (Mouse) |
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| | Chr. | Chromosome 5 (mouse) |
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| | Band | 5 G2|5 74.63 cM | Start | 134,518,237 bp |
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| End | 134,581,288 bp |
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| RNA expression pattern |
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| Bgee | | Human | Mouse (ortholog) |
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| Top expressed in | - C1 segment
- ganglionic eminence
- dorsal motor nucleus of vagus nerve
- prefrontal cortex
- inferior olivary nucleus
- optic nerve
- right frontal lobe
- Amygdala
- Brodmann area 10
- postcentral gyrus
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| | Top expressed in | - dentate gyrus of hippocampal formation granule cell
- superior frontal gyrus
- primary visual cortex
- ventricular zone
- supraoptic nucleus
- molar
- granulocyte
- cerebellar cortex
- neural layer of retina
- genital tubercle
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| | More reference expression data |
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| BioGPS | |
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| Wikidata |
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CAP-Gly domain-containing linker protein 2 is a protein that in humans is encoded by the CLIP2 gene.
The protein encoded by this gene belongs to the family of cytoplasmic linker proteins, which have been proposed to mediate the interaction between specific membranous organelles and microtubules. This protein was found to associate with both microtubules and an organelle called the dendritic lamellar body. This gene is hemizygously deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.
