Calponin 1

CNN1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WYP
Identifiers
Aliases	CNN1, HEL-S-14, SMCC, Sm-Calp, calponin 1
External IDs	OMIM: 600806; MGI: 104979; HomoloGene: 995; GeneCards: CNN1; OMA:CNN1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	11,550,323 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	22,020,926 bp
RNA expression pattern
	Top expressed in
	saphenous vein; ; popliteal artery; ; tibial arteries; ; body of uterus; ; tail of epididymis; ; right coronary artery; ; seminal vesicula; ; gastric mucosa; ; myometrium; ; urethra;
	Top expressed in
	ascending aorta; ; tunica media of zone of aorta; ; cervix; ; aortic valve; ; umbilical cord; ; left colon; ; seminal vesicula; ; pyloric antrum; ; atrium; ; migratory enteric neural crest cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	actin binding; calmodulin binding; protein binding;
Cellular component	cytoskeleton; focal adhesion;
Biological process	actomyosin structure organization; regulation of smooth muscle contraction; negative regulation of vascular associated smooth muscle cell proliferation;
	Sources:Amigo / QuickGO
Orthologs
	1264
	12797
	ENSG00000130176
	ENSMUSG00000001349
	P51911
	Q08091
	NM_001299; NM_001308341; NM_001308342
	NM_009922
	NP_001290; NP_001295270; NP_001295271
	NP_034052
	Wikidata
View/Edit Human	View/Edit Mouse

Calponin 1 is a basic smooth muscle protein that in humans is encoded by the CNN1 gene.

The CNN1 gene is located at 19p13.2-p13.1 in the human chromosomal genome and contains 7 exons, encoding the protein calponin 1, an actin filament-associated regulatory protein. Human calponin 1 is a 33.2-KDa protein consists of 297 amino acids with an isoelectric point of 9.1, thus calponin 1 is also known as basic calponin.